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    Neurokinins are a family of small protein-like molecules, or neuropeptides, that serve as signaling molecules throughout the body. These compounds play an important role in communication …

    DESCRIPTION ulifaceted roles in pain transmission, inflammation, and other physiological functions. It is a member of the tachykinin f mily and is synthesized and released by sensory …

    The sensory function of substance P is thought to be related to the transmission of pain information into the central nervous system. Substance P coexists with the excitatory …

    The substance P–NK1 (SP-NK1) receptor system is the most extensively studied NK pathway, and in contrast to receptors for other neurotransmitters, such as glutamate, which have high …

    4 thg 8, 2025 · Substance P is an undecapeptide belonging to the tachykinin neuropeptide family. It functions as a neurotransmitter and neuromodulator. Substance P: Acts on NK1 receptors in …

    31 thg 7, 2024 · Substance P is a potent vasodilator, inducing hypotensive responses via NK1R activation and nitric oxide release. In cerebral arteries, substance P release results in …

    Central and peripheral expression of neurokinin‐1 and neurokinin‐3 receptor and substance P‐encoding messenger RNAs: peripheral regulation during formalin‐induced inflammation and …

    8 thg 10, 2022 · Substance P (SP), the first isolated neuropeptide, belongs to the family of tachykinin peptides and is the natural ligand of neurokinin-1 receptors (NK-1R), also named SP …

    When tissue damage occurs or harmful stimuli are detected, nociceptors release substance P, which then binds to neurokinin receptors on neighboring neurons. This binding amplifies the …

    28 thg 7, 2025 · Substance P is a neuropeptide, a signaling molecule composed of amino acids, found throughout the body. It is particularly concentrated within the nervous system, including …

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